Version 1.0
1. Introduction
Modern scientific laboratories may be associated with a variety of hazards arising from hazardous chemicals, infectious agents, ionizing and non-ionizing radiation sources, etc. Risk assessment, as one of the essential elements of laboratory safety management, shall be adopted as a tool for assessing the potential risks in connection with these hazards. This document briefly explains the assessment procedures and provides guidance for
completing HKSTP’s Risk Assessment Form.
2. Hazard and Risk
A hazard is any source of potential damage, harm or adverse effects on something or someone.
Risk is the chance or probability that a person will be harmed or experience an adverse health effect if exposed to a hazard. It may also apply to situations with property or equipment loss, or harmful effects on the environment. It may also be elaborated as:
Risk = Severity of hazard x Probability of occurrence
3. Risk Assessment Procedures
A simple five steps method for risk assessment is introduced in this document. These five steps are explained as follows:
3.1. Identify the hazards:
3.2. Decide who may be harmed:
3.3. Evaluate the risks
3.4. Record your findings: Use HKSTP’s Risk Assessment Form (SHE Form L05, Part II of SHE Handbook) to record the findings.
Fill in the necessary information as well as assessment results:
3.5. Review your risk assessment: Laboratory setups, including equipment, materials, or procedures, may subject to frequent changes that could lead to new hazards. Risk assessments should be reviewed annually. It also makes sense to review what you are doing on an ongoing basis, look at your risk assessment again and ask yourself:
Have there been any significant changes?
Are there improvements you still need to make?
Have the laboratory workers spotted a problem?
Have you learnt anything from accidents or near misses?
Make sure your risk assessment stays up to date.
4. Risk Matrix
Risk matrix is used as a tool in the process of qualitative risk assessment. A two dimensional 5x5 risk matrix is adopted in HKSTP’s Risk Assessment Form. The likelihood or probability of an occurrence is expressed along the Y axis whereas its severity of consequences on the X axis. For the 5x5 matrix, there are 5 levels of likelihood and 5 levels of severity, each of which has an index (from 1 to 5) as described below. The higher index represents greater likelihood or higher severity for an occurrence. Final risk rating for the specific occurrence is obtained by multiplying these two indexes. To facilitate the implementation of suitable remedial action, the risk rating is grouped into 4 categories:
| Risk Matrix | |||||
| Severity of Consequences | |||||
| Likelihood of Occurence | Insignificant [1] | Minor [2] | Moderate [3] | Major [4] | Catastrophic [5] |
| Rare [1] | 1 | 2 | 3 | 4 | 5 |
| Unlikely [2] | 2 | 4 | 6 | 8 | 10 |
| Possible [3] | 3 | 6 | 9 | 12 | 15 |
| Likely [4] | 4 | 8 | 12 | 16 | 20 |
| Almost certain [5] | 5 | 10 | 15 | 20 | 25 |
| Severity Table | Likelihood Table | ||
| Severity Index (S) | Description | Likelihood Index (L) | Description |
| 5 | Catastrophic (could result in death or permanent total disability, irreversible severe environmental damage, huge financial loss) | 5 | Almost certain (Is expected to occur in most circumstances) |
| 4 | Major (could result in serious injury or occupational illness, significant impact to the environment, major financial loss) | 4 | Likely (Will probably occur in most circumstances) |
| 3 | Moderate (could result in minor to moderate injury or illness, considerable impact to the environment, medium financial loss) | 3 | Possible (Might occur at some time) |
| 2 | Minor (could result in minor injury or illness, environmental impact, or financial loss) | 2 | Unlikely (Could occur at some time) |
| 1 | Insignificant (No injuries, low financial loss) | 1 | Rare (May occur only in exceptional circumstances) |
5. Common Laboratory Hazards and their Control Measures
To facilitate HKSTP’s clients in carrying out risk assessments in laboratories, many common laboratory hazards and their suggested control measures are enlisted in Annex 1. However, it is important to note that this guidance does not identify all possible hazards. Assessors should ensure that they have identified all the hazards that are associated with their particular laboratory activities and devise suitable control measures.
Annex 1. Common Laboratory Hazards and their Control Measures
1. Hazardous Chemicals and Drugs
| Hazard | Suggested Control Measures (Not Exhaustive) |
|---|---|
|
Fire / explosion caused by flammable or unstable chemicals |
|
|
Exposure to hazardous |
Handle hazardous chemicals in fume hoods. |
|
Exposure to nanomaterials |
Nanomaterials which may become airborne are handled in proper enclosure such as fume hood equipped with HEPA filter, biosafety cabinet, etc. |
2. Compressed Gas Cylinders and Cryogens
| Hazard | Suggested Control Measures (Not Exhaustive) |
|---|---|
|
Fire / explosion caused by flammable gases |
Laboratory areas are well ventilated. Gas detectors are installed for gas leakage monitoring. Flammable arrestors are installed where necessary. Regular checking for gas leakage is in place. Proper firefighting equipment is available in the vicinity. |
|
Exposure to hazardous gases |
Laboratory areas are well ventilated Gas cylinders with toxic gases are kept in proper gas cabinets whenever necessary. Gas detectors are installed for gas leakage monitoring whenever necessary. Regular checking for gas leakage is in place. |
|
Cold burn due to exposure to cryogens such as liquid nitrogen |
Wear goggles, face shield and cryogenic gloves when handling cryogens. Transport cryogens carefully in appropriate dewar flasks or containers. |
|
Asphyxiation caused by accumulation of cryogenic gases |
Handle cryogens in well ventilated area. Monitor the ambient oxygen level using appropriate oxygen detector. |
3. Biological Agents
| Hazard | Suggested Control Measures (Not Exhaustive) |
|---|---|
|
Exposure to infectious agents |
Emergency facilities including firefighting equipment, emergency shower / eyewash unit, spill kit and first aid kit must be available in the vicinity. |
|
Injury caused by animal bites or scratches |
Wear appropriate gloves when handling animals. Use proper animal restrainers. Handle animals carefully following standard practices. |
|
Needle-stick injury |
Avoid re-capping needles. Substitute needles by other devices as far as possible. |
Risk Matrix |
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|
|
Severity of Consequences |
||||
Likelihood of Occurrence |
Insignificant [1] |
Minor [2] |
Moderate [3] |
Major [4] |
Catastrophic [5] |
Rare [1] |
1 |
2 |
3 |
4 |
5 |
Unlikely [2] |
2 |
4 |
6 |
8 |
10 |
Possible [3] |
3 |
6 |
9 |
12 |
15 |
Likely [4] |
4 |
8 |
12 |
16 |
20 |
Almost certain [5] |
5 |
10 |
15 |
20 |
25 |